Dr. Sebastian A.J. Zaat is Principal Investigator of the research line “Biomaterial-associated infection and novel antimicrobial strategies” of the Amsterdam UMC, University of Amsterdam, The Netherlands. His research is focused on pathogenesis, prevention and treatment of biomaterial-associated infections, both in soft tissue (catheters, surgical meshes) and bone (implants, fixation devices). Based on a thorough understanding of the events leading to infection, novel strategies are being developed including rapid microbial diagnosis, anti-infective coatings not subject to bacterial resistance development, prevention of biofilm formation, and enhancement of killing of bacteria hiding in tissue surrounding inserted or implanted medical devices. These approaches are aimed at maximally reducing the risk of infection for patients which depend on such medical devices.


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